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陳堅
發布日期:2020-04-09   浏覽次數:

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個人信息

陳堅,博士,博導,教授

Email: jianchen (at) ujs.edu.cn

教育背景

2003.9-2007.7 浙江工業大學, 學士

2007.9-2010.7 南京農業大學, 碩士

2010.10-2014.10 意大利維羅納大學,博士

工作經曆

2015.1-2019.9 美國南卡羅萊納大學,博士後

2020.4-現在 世界杯正规买球app,金山青年特聘教授,世界杯正规买球app特聘教授

榮譽稱号

江蘇特聘教授

學術兼職

Plant Physiology, Assistant Features Editor

Frontiers in Plant Science, Guest Associate Editor

Frontiers in Microbiology, Guest Associate Editor

課題組網頁:

https://www.x-mol.com/groups/jian_chen

代表性文章: (#共同第一作者,*通訊作者)

2023

  • Sharifi R, Chen J, Sun Z, Chen J*. Conferring resistance to parasitic witchweed by shifting strigolactone biosynthesis. Trends Parasitol. 2023 May 10:S1471-4922(23)00101-0.

  • Chen J*, Chen J, Sun Z. Staying vigilant: NLR monitors virus invasion. Trends Plant Sci. 2023 Mar 17:S1360-1385(23)00091-2.

  • Islam F, Khan MSS, Ahmed S, Abdullah M, Hannan F, Chen J*. OsLPXC negatively regulates tolerance to cold stress via modulating oxidative stress, antioxidant defense and JA accumulation in rice. Free Radic Biol Med. 2023 Feb 10;199:2-16 (一區top期刊)

  • Fang Y, Chen J*. Changing the script: A Phytophthora sojae effector hijacks RNA-binding proteins to reprogram plant immunity. Plant Physiol. 2023 Feb 12;191(2):820-822.

2022

  • Chen J*. Need help? Recently identified phosphorylation targets of MAP kinase 4 aid plant immunity. Plant Physiol. 2022 Aug 9:kiac366.(一區,Top期刊,IF=8.0)

  • Chen R#, He J#, Su Z*, Chen J*. A plant immune protein fights against cancer. Trends Biochem Sci. 2022 Aug 16:S0968-0004(22)00196-7. (一區,Top期刊,IF=14.26)

  • Kui L#, Majeed A#, Ahmed S, Khan MSS, Islam F, Chen J*, Dong Y*. Solanum tuberosum (potato). Trends Genet. 2022 Jul 9:S0168-9525(22)00168-8.(一區,Top期刊,IF=11.82)

  • Chen J*. Bringing it in: a transporter of extracellular amino acids for regulation of plant immunity. Plant Physiol. 2022 Jun 25:kiac310. (一區,Top期刊,IF=8.0)

  • Ahmed S, Chen J*. Transcription factor OsNAC016: a convergent point of brassinosteroid and abscisic acid signaling in rice. Plant Physiol. 2022 Apr 23:kiac185.(一區,Top期刊,IF=8.0)

  • Khan MSS#, Islam F#, Ye Y, Ashline M, Wang D, Zhao B, Fu ZQ*, Chen J*. The Interplay between Hydrogen Sulfide and Phytohormone Signaling Pathways under Challenging Environments. Int J Mol Sci. 2022, 23(8), 4272 (二區,Top期刊,IF=6.21)

  • Chen H#, Chen J#, Zhao Y, Liu F*, Fu ZQ*. Pseudomonas syringae pathovars. Trends Microbiol. 2022 Mar 26:S0966-842X(22)00064-6. (一區,Top期刊,IF=18.23)

  • Khan MSS, Chen J*. Regulation of the interplay between reactive oxygen species and SUMOylation pathways: an essential role for SIZ1. Plant Physiol. 2022 Mar 11:kiac110.(一區,Top期刊,IF=8.0)

  • Khan MSS#, Islam F#, Chen H, Chang M, Wang D, Liu F*, Fu ZQ*, Chen J*. Transcriptional Coactivators: Driving Force of Plant Immunity. Front Plant Sci. 2022 Jan 28;13:823937. (一區,Top期刊,IF=6.6.)

  • Chen J#, Sharifi R#, Khan MSS#, Islam F, Bhat JA, Kui L*, Majeed A*. Wheat Microbiome: Structure, Dynamics, and Role in Improving Performance Under Stress Environments. Front Microbiol. 2022 Jan 13;12:821546. (二區,Top期刊,IF=6.06)

  • Chen J, Chen H, Liu F*, Fu ZQ*. A war on the cell wall. Mol Plant. 2022 Feb 7;15(2):219-221. (一區,Top期刊,IF=21.95)

  • Chen J, Sharifi R*, Ryu CM*. Turning a bacterial gaseous virulence trigger off. Trends Plant Sci. 2022 Jan;27(1):4-6. (一區,Top期刊,IF=22.01)

2021

  • Chen J, Daowen Wang*, Fu ZQ*. Degradation without Ubiquitination: New Function of a Parasite Effector. Trends Parasitol. 2021 Dec;37(12):1024-1026. (一區,Top期刊,IF=10.53)

  • Chen J, Zhou H, Xie Y*. SnRK2.6 phosphorylation/persulfidation: where ABA and H2S signaling meet. Trends Plant Sci. 2021 Dec;26(12):1207-1209. (一區,Top期刊,IF=22.01)

  • Kong M, Sheng T, Liang J, Ali Q, Gu Q, Wu H, Chen J*, Liu J*, and Gao X*. Melatonin and Its Homologs Induce Immune Responses via Receptors trP47363-trP13076 in Nicotiana benthamiana. Front Plant Sci. 2021 Jun 30;12:691835. (二區,Top期刊,IF=6.63)

  • Chen J#, Li M#, Liu L, Chen G*, Fu ZQ*. ZAR1 Resistosome and Helper NLRs: Bringing in Calcium and Inducing Cell Death. Mol Plant. 2021 Aug 2;14(8):1234-1236. (一區,Top期刊, IF=21.95)

  • Wang X#, Chen J#, Liu N*, Fu ZQ*. Dual Functions of a Stable Peptide against Citrus Huanglongbing Disease. Trends Plant Sci. 2021 Jul;26(7):668-670 (一區,Top期刊, IF=22.01)

  • Chen J#*, Zhang J#, Kong M#, Freeman A, Chen H*, Liu F*. More stories to tell: NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1, a salicylic acid receptor. Plant Cell Environ. 2021 Jun;44(6):1716-1727.(一區,Top期刊, IF=7.95)

2020

  • Chen J, Clinton M, Qi G, Wang D, Liu F*, and Fu ZQ*. Reprogramming and remodeling: transcriptional and epigenetic regulation of salicylic acid-mediated plant defense. J Exp Bot. 2020 Aug 17;71(17):5256-5268. (一區,Top期刊, IF=6.99)

2019

  • Chen J, Mohan R, Zhang Y, Li M, Chen H, Palmer IA, Chang M, Qi G, Spoel SH, Mengiste T, Wang D, Liu F*, Fu ZQ*. NPR1 Promotes Its Own and Target Gene Expression in Plant Defense by Recruiting CDK8. Plant Physiol. 2019 Sep;181(1):289-304. (一區,Top期刊, IF=6.9) (高被引)

2018

  • Qi G#, Chen J#, Chang M#, Chen H, Hall K, Korin J, Liu F*, Wang D*, Fu ZQ*. Pandemonium Breaks Out: Disruption of Salicylic Acid-Mediated Defense by Plant Pathogens. Mol Plant. 2018 Dec 3;11(12):1427-1439. (一區,Top期刊,IF=10.8)

2016

  • Hussain J#, Chen J#, Locato V#, Sabetta W#, Behera S, Cimini S, Griggio F, Martínez-Jaime S, Graf A, Bouneb M, Pachaiappan R, Fincato P, Blanco E, Costa A, De Gara L, Bellin D*, de Pinto MC, Vandelle E*. Constitutive cyclic GMP accumulation in Arabidopsis thaliana compromises systemic acquired resistance induced by an avirulent pathogen by modulating local signals. Sci Rep. 2016 Nov 4;6:36423. (二區,IF=4.2)

2014

  • Chen J#, Vandelle E#, Bellin D, Delledonne M*. Detection and function of nitric oxide during the hypersensitive response in Arabidopsis thaliana: where there's a will there's a way. Nitric Oxide. 2014 Dec 1;43:81-8.(二區,IF=3.5)

2009

  • 陳堅, 耿貝貝, 沈文飚, 黃麗琴 (2009) 一氧化碳在植物體内的信号轉導作用。生命的化學 29: 283-286

Book Chapter

  • Chen J, Bellin D, Vandelle E. Measurement of Cyclic GMP During Plant Hypersensitive Disease Resistance Response. Methods Mol Biol. 2018;1743:143-151.

參與發表的文章

  • Qi G, Chen H, Wang D, Zheng H, Tang X, Guo Z, Cheng J, Chen J, Wang Y, Bai MY, Liu F, Wang D, Fu ZQ. The BZR1-EDS1 module regulates plant growth-defense coordination. Mol Plant. 2021 Dec 6;14(12):2072-2087.

  • Zhang R, Chen J, Wang D, Fu ZQ. Hijacking of host mitochondria by Toxoplasma gondii and SARS-CoV-2. Trends Parasitol. 2022 Feb 8:S1471-4922(22)00032-0

  • Kui L, Chen B, Chen J, Sharifi R, Dong Y, Zhang Z, Miao J. A Comparative Analysis on the Structure and Function of the Panax notoginseng Rhizosphere Microbiome. Front Microbiol. 2021 Jun 9;12:673512.

  • Palmer IA, Chen H, Chen J, Chang M, Li M, Liu F, Fu ZQ. Novel Salicylic Acid Analogs Induce a Potent Defense Response in Arabidopsis. Int J Mol Sci. 2019 Jul 8;20(13).

  • Chang M, Zhao J, Chen H, Li G, Chen J, Li M, Palmer IA, Song J, Alfano JR, Liu F, Fu ZQ. PBS3 Protects EDS1 from Proteasome-Mediated Degradation in Plant Immunity. Mol Plant. 2019 Feb 11. (IF=12.08)

  • Li M, Chen H, Chen J, Chang M, Palmer IA, Gassmann W, Liu F, Fu ZQ. TCP Transcription Factors Interact With NPR1 and Contribute Redundantly to Systemic Acquired Resistance. Front Plant Sci. 2018 Aug 14;9:1153.

  • Chen H, Palmer IA, Chen J, Chang M, Thompson SL, Liu F, Fu ZQ. Specific and Accurate Detection of the Citrus Greening Pathogen Candidatus liberibacter spp. Using Conventional PCR on Citrus Leaf Tissue Samples. J Vis Exp. 2018 Jun 29;(136).

  • Chen H, Chen J, Li M, Chang M, Xu KM, Shang ZH, Zhao Y, Palmer I, Zhang YQ, McGrill J, Alfano JR, Nishimura MT, Liu FQ, and Fu ZQ. A Bacterial Type III Effector Targets the Master Regulator of Salicylic Acid Signaling NPR1 to Subvert Plant Immunity. Cell Host Microbe. 2017 Dec 13;22(6):777-788 (F1000Prime) (IF=17.9)

  • Kumar N, Astegno A, Chen J, Giorgetti A, Dominici P. Residues in the Distal Heme Pocket of Arabidopsis Non-Symbiotic Hemoglobins: Implication for Nitrite Reductase Activity. Int. J. Mol. Sci. 2016, 17(5), 640

  • Chen XY, Ding X, Xu S, Wang R, Xuan W, Cao ZY, Chen J, Wu HH, Ye MB, Shen WB (2009) Endogenous hydrogen peroxide plays a positive role in the upregulation of heme oxygenase and acclimation to oxidative stress in wheat seedling leaves. J Integr Plant Biol51: 951–960

科研項目

  • 江蘇省自然科學基金面上項目,2021.7-2024.7,主持

  • 國家自然科學基金青年項目,32000201,2021.1-2023.12,24萬元,主持

  • 世界杯正规买球app高級人才啟動基金,20JDG34, 40萬元,主持

  • 南卡羅萊納大學博士後基金Aspire I track II B,Unravel the function of NPR1 interacting La-related proteins in plant defense response, 13010-17-44719,2017.7-2018.9,0.5萬美元,主持。

  • 國家自然科學基金青年項目,新型植物免疫複合體PBS3-EDS1促進植物抗病性機制研究,31701863,2018.1-2020.12,25萬元,參與, 第二,已結題

  • 美國國家自然科學基金,Targeting of salicylic acid-activated NPR1 by a bacterial type III effector,1758994,2018.8.1-2021.7.31,49.3萬美元,參與,第三,已結題

  • 美國國家自然科學基金,Salicylic acid signaling in plant pathogen interactions,13010-FC43,2015.8.1-2016.7.3,14.8萬美元,參與,第二

  • 國家自然科學基金面上項目,水稻白葉枯病菌中一個新緻病因子受寄主誘導及其調控緻病性的機制研究,31571974,2016.1-2019.12,65萬元,參與,第三

研究方向

1、水楊酸信号重要組分、轉錄中介體、表觀遺傳調控因子在植物免疫中的作用

2、丁香假單胞三型效應因子與植物免疫蛋白的互作

3、EDS1/NPR1互作蛋白在植物免疫中的作用

4、水稻在生物脅迫及非生物脅迫中的響應

本課題組長期招聘博士後,助理研究員,副研究員,同時歡迎碩士生及博士生的加入

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